| ncRNA name | hsa-miR-20a |
| ncRNA Category | miRNA |
| Disease name | retinoblastoma (RB) |
| Species | Homo sapiens |
| Tissues/Cell_line | human RB cell line Y79 |
| Methods | MTT assay, BrdU incorporation assay, qRT-PCR |
| Expression pattern | down-regulated |
| Functional description | To study the ability of the SD-208 as a potential anticancer agent via changing oncogene/tumor suppressor miRNAs, the researchers partially evaluated its effects on some miRNA expression. SD-208 could significantly upregulate miR-18a, 22a, and 34a (P<0.05) while downregulating miR-20a (P<0.05) expression in retinoblastoma cells. |
| PubMed ID | 27306340 |
| Year | 2016 |
| Title | Evaluation of SD-208, a TGF-β-RI Kinase Inhibitor, as an Anticancer Agent in Retinoblastoma. |
| Drug-related ncRNA | YES (SD-2NO8) |
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